Filed under: Lofepramine (Lomont)

From Paxil to Effexor XR

Effexor XR is a medication used to treat depression and anxiety disorders. Buy effexor medication and feel better today!

Question:

Hi ppl, I’m (24, m) thinking about switching from Paxil (20mg/day) to Effexor-XR coz I have side-effects like probs getting an erection, beeing sleepy all day and getting to sleep at night. Erection can be solved with Viagra 25, sleeping problems with Stilnoc. I’m taking Paxil since 10 months, it’s really working well beside of the s-e. So, here r my questions: 1. How long does it take Effexor to work.    (I know that it might not work, since Prozac had no effect) 2. What dose should I use for depression? 3. Did anybody did that before and has any tips? Thx in advance. — Have A Nice Day Peter ICQ-UIN:  1494438       Homepage: http://www.p-loeffler.de Billiger Telefonieren? http://blitztarif.de

Response:

Hi I’m starting Effexor XR 75mg this week after 12 months on lofepramine (UK) for same reason. Jim

Response:

- Hide quoted text — Show quoted text – > Hi ppl, > I’m (24, m) thinking about switching from Paxil (20mg/day) to > Effexor-XR coz I have side-effects like probs getting an erection, > beeing sleepy all day and getting to sleep at night. > Erection can be solved with Viagra 25, sleeping problems with Stilnoc. > I’m taking Paxil since 10 months, it’s really working well beside of > the s-e. > So, here r my questions: > 1. How long does it take Effexor to work. >    (I know that it might not work, since Prozac had no effect) > 2. What dose should I use for depression? > 3. Did anybody did that before and has any tips? > Thx in advance.

Hi, there.  My current med regimen consists of 400mg tegretol, 25mg of topamax, and 37.5mg of effexor.  I’ve been on effexor for a couple of months and it’s my favorite.  I’ve went up to 150mg before and at that dosage, I get a little lethargic.  (I’m on two other mood stabilizers, though.)  So that probably contributes to my somnolence.  Anyway, here’s my answers: 1. Some people see results immediately; others see results in a week. However, it’s always a good idea to give your body at least six weeks to see how it will work. 2. I’m doing okay at 37.5mg with my epilepsy meds.  My pdoc tells me that most people get relief at 75mg.  However, you can go up to 300mg if your still depressed.  In extreme cases you can go up to 375mg.  It is also important to note that many people have a raise in blood pressure when hitting the higher doses.  (About 150mg according to documentation.) Hope this helps a little. Jeremy

Response:

Hya Peter I’m 30, female, so there is a difference to start with! ;) Sorry you have been having problems with Paxil.  I have never been on Paxil so I can’t comment on the drug at all. I am on 300mg of effexor just now.  I started on 75mg and gradually increased the dosage.  I think it started working quite quickly, although I am also on flupenthixol, which although an anti-psychotic, is actually a fast-acting anti-depressant. I expect that you would start on either 37.5 or 75mg and then it would be increased if necessary.  Different people react to different dosages, so it’s trial and error to be honest.  Dont increase your dose unless you have talked it over with your GP or your psych. Effexor has been beneficial to me and I am now living life again as I should be and I can see a future, something that has been lacking in my life for too many years.  I hope it affects you in the same way :) Good luck with the effexor. lisa xxx

– Hide quoted text — Show quoted text -> Hi ppl, > I’m (24, m) thinking about switching from Paxil (20mg/day) to > Effexor-XR coz I have side-effects like probs getting an erection, > beeing sleepy all day and getting to sleep at night. > Erection can be solved with Viagra 25, sleeping problems with Stilnoc. > I’m taking Paxil since 10 months, it’s really working well beside of > the s-e. > So, here r my questions: > 1. How long does it take Effexor to work. >    (I know that it might not work, since Prozac had no effect) > 2. What dose should I use for depression? > 3. Did anybody did that before and has any tips? > Thx in advance. > — > Have A Nice Day > Peter > ICQ-UIN:  1494438 > Homepage: http://www.p-loeffler.de > Billiger Telefonieren? http://blitztarif.de

Response:

Leave a Comment May 22, 2001

SSRI's and psychedelics

Question:

snip >… I’d finished my thesis on the long tern effects >of THC on the serotonin receptors!

 Care to elaborate or point to some sources on this ? thanks, paul

Response:

Er, sorry. I’ll have to take the 5th on that one….

Response:

- Hide quoted text — Show quoted text – > No one ever gave me that explaination before but I had done a > considerable amount of LSD in my youth and coincidentally am unable to > take SSRI’s.  They caused mania and/or hallucinations.  I was told > only that certain BP’s can’t take/tolerate them.   > One pdoc suggested during the Dx period that my reaction to SSRI’s did > "indicate" manic depressive illness.  This I do not fully understand > since some BP’s obviously benefit from SSRI’s. > Things that make you go "Hmmm." >My pdoc said I was not a good candidate for Prozax, Zoloft, etc… because I >have takes LSD more that 60 times. A previous pdoc put me on Zoloft and it did >make me manic. Anyone else hear of this? > To reply via e-mail, remove the numbers from my name. > National Depression Manic Depression Association > (NDMDA)  1-800-826-3632 > There are local chapters in many states which can > point you to a local support group.

Response:

I’ve never done LSD (waving hand in the air). I smoked pot a few times in high school. At first it did what it was supposed to but then it started to feel like either I was going into shock or having a seizure or soemthing weird and scary. I almost fell out a window and looked like a zombie. sooooooooooooo. I stay off of drugs and carefully take my meds from the good docta. I am sensitive to everything it seems. drugs are bad for you. >:/

muy mal. ‘lissa-cat

Response:

LSD not euphoric? Hahahahahahahahahahahahahahaha. No, you obviously haven’t taken it. Not as euphoric as crack though. That’s mania in a pebble. Morgan Clean and serene now, but I’ve had my moments…. – Hide quoted text — Show quoted text ->Gee, I feel like the minority here.  Has everyone taken LSD here?  I >know it is partially a function of my age (27), but I never did. >Not me, although I have plenty of drug-taking friends. >enough and LSD might have been the last straw.  That "Wheee" feeling >of SSRI’s in the beginning is like LSD?  Boy did I miss something. >You missed the chance to fry your brain more. I haven’t heard anyone >describe LSD as euphoric, just hallucinogenic. >marco >marco anglesio mpa at squawk dot ml dot org   | Life would be tolerable >visit squawk: http://squawk.ml.org            | but for its amusements. >read SURFACE: http://asus.queensu.ca/~surface | — G. B. Shaw

Response:

>  Gee, I feel like the minority here.  Has everyone taken LSD here?

I tried it once, and found it to be just like getting stoned, except far more intensely so. As I found grass to be sufficient escape, offering me greater control over titration (I wouldn’t have expressed it that way back then) and I didn’t know anyone who jumped out a window after smoking a joint, I never did LSD again. I haven’t smoked grass for years. Now that I’m diagnosed and taking prescription meds, it doesn’t seem like a good idea. Yet I must say it relieved my depression far more reliably than any prescription drug I’ve used (which now that I mention it, no meds have ever relieved depression at all). I wouldn’t have wanted to drive a car stoned, and you wouldn’t want me programming your computer stoned. Then again, when I’m depressed who wants to do those things anyway? Stuck looking for my time machine now

Response:

Ta Da!!! I have never taken LSD either!!! Was always ( for some reason ) scared of the outcome. I think in the back of my mind ( if I do in fact have one ) I knew it either wouldn’t do anything or tilt me into oblivion. You are not alone!!! I do on the other hand consume everything else I could possibly find. Earl, straight, sober ( yes me ), and drug free…well except for meds…hehehe… – Hide quoted text — Show quoted text ->snip<

Response:

No drugs for me either.  Alchohol sent me to the netherworld so I was terrified what drugs would do…. Cher who would just as soon skip the bipolar too.

Response:

I do on the other hand consume everything else I could possibly >find.

Ya gotta laugh at yourself sometimes…that should say I "DID" consume…LMAO… – Hide quoted text — Show quoted text ->Earl, straight, sober ( yes me ), and drug free…well except for >meds…hehehe…

Response:

Hahahaha. Love your thoughts on talking to the kids. My 13 year old step-son started talking about drugs the other day and I found myself answering all his questions with the sort of expert detail usually reserved for academics on the Open University (TV-based Uni. in Britland). I thought his eyes looked a little wide after I’d finished my thesis on the long tern effects of THC on the serotonin receptors! Either he was [a] impressed by my perspicacity, [b] stoned, or [c] a penny dropped that step-dad was a little too experienced about these matters! Morgan Clean and serene, who had nothing but good trips 20 years ago but whose memory is now akin to that of a goldfish   ; o – Hide quoted text — Show quoted text ->Gee, I feel like the minority here.  Has everyone taken LSD here?  I >know it is partially a function of my age (27), but I never did.  It >was the drug of choice when I was in high school and I could have had >it, but I had a feeling that my brain chemistry was already unbalanced >enough and LSD might have been the last straw.  That "Wheee" feeling >of SSRI’s in the beginning is like LSD?  Boy did I miss something. >But then again a friend thought her god was raping her on her frist >trip.  Not exactly a shining endorsment, huh? >Kimberly, now trying to be a respectable mother of two and who can >truly answer her kid’s question, "Mom, did you ever do drugs?" with a >no, and wants to keep that answer the way it is.  Now I just have to >hope they don’t ask about sex, why I left home before I finished high >school, etc.

Response:

>Gee, I feel like the minority here.  Has everyone taken LSD here?  I >know it is partially a function of my age (27), but I never did.  

Not me, although I have plenty of drug-taking friends. >enough and LSD might have been the last straw.  That "Wheee" feeling >of SSRI’s in the beginning is like LSD?  Boy did I miss something.

You missed the chance to fry your brain more. I haven’t heard anyone describe LSD as euphoric, just hallucinogenic. marco marco anglesio mpa at squawk dot ml dot org   | Life would be tolerable   visit squawk: http://squawk.ml.org            | but for its amusements. read SURFACE: http://asus.queensu.ca/~surface | — G. B. Shaw

Response:

Gee, I feel like the minority here.  Has everyone taken LSD here?  I know it is partially a function of my age (27), but I never did.  It was the drug of choice when I was in high school and I could have had it, but I had a feeling that my brain chemistry was already unbalanced enough and LSD might have been the last straw.  That "Wheee" feeling of SSRI’s in the beginning is like LSD?  Boy did I miss something. But then again a friend thought her god was raping her on her frist trip.  Not exactly a shining endorsment, huh? Kimberly, now trying to be a respectable mother of two and who can truly answer her kid’s question, "Mom, did you ever do drugs?" with a no, and wants to keep that answer the way it is.  Now I just have to hope they don’t ask about sex, why I left home before I finished high school, etc.

Response:

I forgot to mention that she recommended Wellbutrin since it acts on a different chemical system in the brain. I am also taking Depakote and Klonopin with great success but the Wellbutrin started making me too wired. When I first started taking the Zoloft way back when, (the very first day), it felt like I was coming on to an acid trip. Colors seemed brighter. I wasn’t unhappy about it at the time ;-) . – Hide quoted text — Show quoted text -> My pdoc said I was not a good candidate for Prozax, Zoloft, etc… because I > have takes LSD more that 60 times. A previous pdoc put me on Zoloft and it did > make me manic. Anyone else hear of this? >I’ve always wondered about the relationship between psychedelics and mood >swings. I think a lot of trips could possibly push the brain in the direction >of instability, which might not show up until an SSRI activates mania or >hypomania. Tripping is definitely a different space for the mind to be in, >mostly a good one if you don’t overdo it. Maybe 60 trips is just a wee bit >too much.  ; – > >Connie

Response:

> No one ever gave me that explaination before but I had done a > considerable amount of LSD in my youth and coincidentally am unable to > take SSRI’s.  They caused mania and/or hallucinations.  I was told > only that certain BP’s can’t take/tolerate them.

I’ve been interested in the connection between SSRIs and LSD, since SSRIs cause more of your natural serotonin to stay active, while LSD acts like an artifical super-serotonin. I took LSD about 12 times ten years ago. When I started taking Paxil it was GGGGRRRREEEEAAAATTTT!!!! It was like LSD without the distortion of reality. I’m no stranger to mania either, since I’m a Bipolar I, and the month-long hypomanic episode Paxil put me on was better than any manic episode I’ve ever had naturally. But since that first honeymoon month, I’ve been unable to capture that state again. But at least now I’ve got a clue as to why I had such a wonderful time. Well, I guess I can always take acid. :-) — Utilicom, Inc. Spread Spectrum Communications / (805) 964-5848 x227 323 Love Place                                 FAX (805) 964-5706 Santa Barbara, CA 93117                       / http://www.utilicom.com/                        Yeah, I want Cheesy Poofs!

Response:

> My pdoc said I was not a good candidate for Prozax, Zoloft, etc… because I > have takes LSD more that 60 times. A previous pdoc put me on Zoloft and it did > make me manic. Anyone else hear of this?

I’ve always wondered about the relationship between psychedelics and mood swings. I think a lot of trips could possibly push the brain in the direction of instability, which might not show up until an SSRI activates mania or hypomania. Tripping is definitely a different space for the mind to be in, mostly a good one if you don’t overdo it. Maybe 60 trips is just a wee bit too much.  ; – > Connie

Response:

Ah the wonder of diversity. Everyone has their experiences and they are all subtly different. I too did a lot of LSD in the 70’s. SSRIs, in my case Lustral (AKA Zoloft), did sort of work for a while, but only in combination with Lofepramine. (I was also taking Lithium and Tegretol.) I took the Lofepramine all the time, only adding the Lustral when I began to feel depression coming on. The combination brought the therapeutic delay down from 4 weeks to 7 days. Unfortunately, a new pdoc – a regular occurrence under the UK NHS  :  (  - didn’t like the combination, for reasons I have never established, and prescribed increased Lustral without the Lofepramine. Result: 4 month depression last autumn, the longest since I started successfully managing BP 4 years ago. Finally the combination of Effexor, dropping the Lithium and Tegretol, and mild sleep deprivation relieved the depression. Since then, I have continued the Effexor, treated hypomania with Mellarill, and added back Lithium at a lower level. I am currently considering Switching from Lithium to Depakote as I am quite *attached* to my kidneys and have been on Lithium for 11 years. Also because, with the Effexor, I have started to cycle more rapidly (though nothing like so severely  : ) ) and Depakote is the recommended First Line med for rapid cyclers ( according to the Expert Consensus – http://www.psychguides.com/eks_bpgl.htm  ). Effexor is similar to the SSRIs but worked on noradrenalin as well as serotonin. Works for me anyway… All the best Morgan

– Hide quoted text — Show quoted text ->No one ever gave me that explaination before but I had done a >considerable amount of LSD in my youth and coincidentally am unable to >take SSRI’s.  They caused mania and/or hallucinations.  I was told >only that certain BP’s can’t take/tolerate them. >One pdoc suggested during the Dx period that my reaction to SSRI’s did >"indicate" manic depressive illness.  This I do not fully understand >since some BP’s obviously benefit from SSRI’s. >Things that make you go "Hmmm." >My pdoc said I was not a good candidate for Prozax, Zoloft, etc… because I >have takes LSD more that 60 times. A previous pdoc put me on Zoloft and it did >make me manic. Anyone else hear of this? >To reply via e-mail, remove the numbers from my name. >National Depression Manic Depression Association >(NDMDA)  1-800-826-3632 >There are local chapters in many states which can >point you to a local support group.

Response:

My pdoc said I was not a good candidate for Prozax, Zoloft, etc… because I have takes LSD more that 60 times. A previous pdoc put me on Zoloft and it did make me manic. Anyone else hear of this?

Response:

No one ever gave me that explaination before but I had done a considerable amount of LSD in my youth and coincidentally am unable to take SSRI’s.  They caused mania and/or hallucinations.  I was told only that certain BP’s can’t take/tolerate them.   One pdoc suggested during the Dx period that my reaction to SSRI’s did "indicate" manic depressive illness.  This I do not fully understand since some BP’s obviously benefit from SSRI’s. Things that make you go "Hmmm." >My pdoc said I was not a good candidate for Prozax, Zoloft, etc… because I >have takes LSD more that 60 times. A previous pdoc put me on Zoloft and it did >make me manic. Anyone else hear of this?

To reply via e-mail, remove the numbers from my name. National Depression Manic Depression Association (NDMDA)  1-800-826-3632 There are local chapters in many states which can point you to a local support group.

Response:

Leave a Comment March 1, 1998


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